Biochemistry and Enzymology
Dr. Armache's Research Interest: Mechanisms and functions of
ATP-dependent chromatin remodeling complexes and their place
in genome regulation
Dr. Bai's Research Interest: Chromatin structure and its role in
gene regulation.
Dr. Bevilacqua's Research Interest: Attaining a molecular level
understanding of RNA in biology.
Dr. Boal's Research Interest: The study of the structural
differences between members of largemetalloenzyme
superfamilies that share common features but promote
different reactionsor use distinct cofactors.
Dr. Bollinger's Research Interest: The understanding of the
relationship between the structures and catalytic mechanisms of
enzymes that employ such clusters, and to elucidate the
biochemical mechanisms by which the proteins acquire their
clusters.
Dr. Booker's Research Interest: Elucidating the chemical
mechanisms by which enzymes containing iron-sulfur clusters
catalyze chemical reactions.
Dr. Bryant's Research Interest: Genomics, structural and
functional relationships, metabolism, physiology and ecology
of chlorophototrophic bacteria.
Dr. Ferry's Research Interest: The study the enzymology and
molecular biology of anaerobic microbes from the Archaea
domain.
Dr. Golbeck's Research Interest: Biophysical studies of electron
transfer mechanisms in photosynthetic prokaryotes.
Dr. Gu's Research Interest: The utilization of biochemical,
molecular genetics, and spectroscopic approaches to
decipher mechanisms of cellulose biosynthesis.
Dr. Hanna-Rose's Research Interest: We use genetic and
metabolomics approaches in C. elegans to model inborn errors
of metabolism and probe the molecular links between metabolic
perturbations and animal behavior and physiology.
Dr. Keiler's Research Interest: Protein quality control, ribosome
rescue, and new antibiotics.
Dr. Kreb's Research Interest: The elucidation of the reaction
mechanisms by which mono- and dinuclear non-heme-iron
enzymes activate dioxygen (O2) for a wide variety of oxidative
transformations.
Dr. Lai's Research Interest: Growth Control and Cancer Genetics.
Dr. Lesk's Research Interest: Computational analysis of protein
structure, function, genomics and evolution.
Dr. Llinás' Research Interest: The combination of tools from
functional genomics, molecular biology, computational biology,
biochemistry, and metabolomics to understand the fundamental
molecular mechanisms underlying the development of this
parasite.
Dr. Meredith's Research Interest: Bacterial cell envelope
biosynthesis.
Dr. Murakami's Research Interest: We apply cryo-EM and X-ray
crystallography techniques to reveal three-dimensional structures
of DNA and RNA polymerases for elucidating the mechanisms of
DNA replication and RNA transcription.
Dr. Okafor's Research Interest: The structural mechanisms of
signaling and regulation in protein complexes.
Dr. Patterson's Research Interest: Understanding the host-
metabolite-microbiota communication network‚ specifically
how the manipulation of gut microbiota by diet and/or
xenobiotics impacts host metabolites (e.g., bile acids, short
chain fatty acids), their metabolism, and how these co-
metabolites interact with host ligand-activated transcription
factors.
Dr. Perdew's Research Interest: The biochemical pathway of
AHR activation and characterized species difference in AHR
mediated transcriptional activation of target genes.
Dr. Peter's Research Interest: The role of the peroxisome
proliferator-activated receptors (PPARs) in the regulation
of homeostasis, toxicology and carcinogenesis.
Dr. Reese's Research Interest: Stress-induced gene expression
and UV resistance pathways, Regulation of mRNAs from birth to
death during stress responses, Targeted protein degradation
during transcriptional stress and How RNA Polymerase II contends
with barriers throughout the genome.
Dr. Roy's Research Interest: Forensic DNA analysis using
massively parallel sequencing and short tandem repeat
technology, trace evidence, fingerprints.
Dr. Showalter's Research Interest: The use of solution
nuclear magnetic resonance (NMR) spectroscopy, in combination
with thermodynamic analysis, chemical biology, and cellular
assays to advance understanding of protein function.
Dr. Szpara's Research Interest: Understanding the consequences
of HSV latency for the neurons that harbor the HSV pathogen
and the search for improved therapeutics using a combination
of virology, neurobiology, next generation sequencing
technologies, and bioinformatics.
Dr. Tan's Research Interest: The understanding of how genes
are regulated by combining genetic, biochemical and structural
descriptions.
Dr. Weinert's Research Interest: The understanding of how
the globin coupled sensor protein family senses oxygen and
transmits the binding signal into downstream events.
