Pho Bui
Office:
209 South Frear Building
Mailing Address:
104 Chemistry Building
University Park, PA 16802
Research Group:
Education:
B.A. Biochemistry, minor in Statistics, Mount Holyoke College, 2016
Honors and Awards:
Harry and Catharine Dalalian Graduate Fellowship, 2017-2018
Homer F. Braddock Scholarship, 2016
Mu Sigma Rho Society by The National Statistics Honorary Society, 2016
Research:
Many biophysical processes, such as protein folding, enzymatic activity and the stability of biopharmaceuticals occur in the crowded cellular environment. This dense matrix is enriched in ions and small organic molecules called osmolytes, which can significantly affect protein stability. In the Cremer group, I am exploring the molecular level mechanisms that govern small molecule and ion-specific interactions that take place in the bulk solution and at biointerfaces through a combination of thermodynamic measurements and vibrational spectroscopy techniques.
Publication:
Bruce, E. E.; Bui, P. T.; Rogers, B. A.; Cremer, P. S.; van der Vegt, N. F. A. Nonadditive Ion Effects Drive Both Collapse and Swelling of Thermoresponsive Polymers in Water. J. Am. Chem. Soc. 2019 (in press).