Department of Chemistry

Biological Chemistry

The Penn State Department of Chemistry has a rich history of research in biological chemistry.  Faculty are engaged in cutting edge research in bioinorganic, biophysical, and computational biology. Researchers have a breadth of interests that range from solving structures of biomolecules to elucidating the mechanism of novel enzymes to looking at protein and RNA folding on a genome-wide scale. Research has applications to numerous organisms, biological pathways, and human diseases.

research

Faculty

Stephen Benkovic Evan Pugh Professor and Eberly Chair in Chemistry

Cellular metabolism and gene replication

Philip Bevilacqua Distinguished Professor of Chemistry and of Biochemistry and Molecular Biology

RNA chemistry and biology

Amie Boal Associate Professor of Chemistry and of Biochemistry and Molecular Biology

Structural Biology and Mechanism of Metalloproteins

David Boehr Associate Professor of Chemistry

The role of protein structural dynamics in enzyme function and regulation

J. Martin Bollinger Professor of Chemistry and of Biochemistry and Molecular Biology

Mechanisms of redox metalloenzymes and metallocofactor assembly

Squire Booker Evan Pugh University Professor of Chemistry and of Biochemistry and Molecular Biology

Biochemistry; enzymology; protein chemistry

Joseph Cotruvo Louis Martarano Career Development Professor of Chemistry

Chemical biology of metal ion and redox homeostasis

Paul Cremer J. Lloyd Huck Professor of Chemistry and of Biochemistry and Molecular Biology

Biological interfaces, nanomaterials, spectroscopy, and microfluidics

Mark Hedglin Assistant Professor of Chemistry

Mechanisms of genome replication

Christine Keating Professor of Chemistry

Bioinspired materials chemistry. Experimental model systems for membraneless organelles and protocells

Carsten Krebs Professor of Chemistry and of Biochemistry and Molecular Biology

Spectroscopic and kinetic studies on the mechanisms of iron-containing enzymes

Tae-Hee Lee Professor of Chemistry

Single molecule biophysics, biochemistry and enzymology

William Noid Professor of Chemistry

Theories of statistical mechanics applied to investigate structural biology

Edward O'Brien Associate Professor of Chemistry and of the Institute for CyberScience

Theory and computation of molecular and cellular processes

Ayusman Sen Verne M. Willaman Professor of Chemistry

Autonomous motion and transport in biological systems

Scott Showalter Professor of Chemistry and of Biochemistry and Molecular Biology

Biophysical chemistry, macromolecular structure and dynamics by NMR

Alexey Silakov Assistant Professor of Chemistry

Metalloezymology and Structural biology

Xin Zhang Paul Berg Early Career Professor of Chemistry and of Biochemistry and of Molecular Biology

Biochemistry of intracellular protein aggregation in stressed proteome and neurodenegeration

Ruobo Zhou Assistant Professor of Chemistry 

Super-resolution fluorescence imaging, single-molecule detection, spatiotemporal organizations of biomolecules, liquid-liquid phase separation in biology, neurobiology, RNA biology.

Courtesy Faculty

John Golbeck Professor of Biochemistry and Biophysics

Research in photosynthesis

Manuel Llinas Professor of Biochemistry and Molecular Biology

Malaria parasite metabolism and biochemistry

Denise Okafor Assistant Professor of Biochemistry & Molecular Biology

Structural mechanisms of signaling and regulation in protein complexes 

Emily Weinert Associate Professor of Biochemistry and Molecular Biology

Bacterial oxygen sensing and atypical cyclic nucleotides